Microarray identification of Carbapanemases, ESBL and AMPC.
All of the clinically prevalent carbapenemase, ESBL and AmpC genes in a single microarray.
Simultaneous detection using up to 100 specific resistance markers, high specificity and sensitivity for all species and accuracy down to a single base pair allows distinguishing ESBL from non-ESBL for TEM and SHV. The automated analysis of results in the software database improves traceability and simplifies data management.
The probe arms will be ligated together only if they match exactly to the template.
A single nucleotide mismatch will prevent ligation of the probe arms.
Only ligated probes are amplified (and labeled).
Different probes will hybridize to different positions on the microarray through the ZIP region of the probe.
Hybridized amplification products are visualized by colorimetric detection.
An image of the microarray, contained in an Array Tube, is generated using the Check-Points Tube Reader.
The E-Ads software automatically analyzes the presence or absence of carbapenemases, AmpCs and ESBLs as well as the resistance genes present.
Check-Points Tube Reader & E-Ads Software
Automatically analyzes the presence of carbapenemases, AmpC and ESBL as well as the resistance genes present.
Software database of results improves traceability and simplifies data management.
OTHER TECHNOLOGY PLATFORMS
Multiplex realtime PCR assays
For active screening and confirmation of carbapenemases and ESBLs in 2 hours.