All of the clinically prevalent carbapenemase, ESBL and AmpC genes in a single microarray.

Simultaneous detection using up to 100 specific resistance markers, high specificity and sensitivity for all species and accuracy down to a single base pair allows distinguishing ESBL from non-ESBL for TEM and SHV. The automated analysis of results in the software database improves traceability and simplifies data management.

1. Identification

  • The probe arms will be ligated together only if they match exactly to the template.
  • A single nucleotide mismatch will prevent ligation of the probe arms.

2. Amplification

  • Only ligated probes are amplified (and labeled).

3. Detection

  • Different probes will hybridize to different positions on the microarray through the ZIP region of the probe.
  • Hybridized amplification products are visualized by colorimetric detection.

4. Analysis

  • An image of the microarray, contained in an Array Tube, is generated using the Check-Points Tube Reader.
  • The E-Ads software automatically analyzes the presence or absence of carbapenemases, AmpCs and ESBLs as well as the resistance genes present.

Check-Points Tube Reader & E-Ads Software

  • Automatically analyzes the presence of carbapenemases, AmpC and ESBL as well as the resistance genes present.
  • Software database of results improves traceability and simplifies data management.


Multiplex realtime PCR assays

For active screening and confirmation of carbapenemases and ESBLs in 2 hours.



Check-Points Health B.V.
Binnenhaven 5
6709 PD Wageningen
The Netherlands

+31 (0) 317 453 908

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