Check-Points employs various technology platforms.

Antimicrobial resistance (AMR) in gram-negative bacteria is genetically very complex. It concerns many different resistance genes and within these genes many different variants exist. Individual resistance genes or variants may be present in a wide range of gram-negative bacteria or may be specific for a single species. Local epidemiology may also differ significantly between various geographical regions. Check-Points employs various technology platforms for testing of AMR gram-negative bacteria depending on the clinical application. For clinical diagnostics the following application may be relevant:

  • Screening of individuals suspected of carrying AMR gram-negatives for infection prevention;
  • Testing individuals infected with gram-negative bacteria for increased resistance against β-lactams;
  • Genotypic confirmation of gram-negative bacteria with elevated resistance in culture-based susceptibility testing;
  • Genotypic profiling of single bacteria for epidemiological typing.


Multiplex real-time
PCR assays

For active screening and confirmation of carbapenemases and ESBLs in 2 hours.


Microarray assays

For comprehensive identification of carbapenemases, ESBLs and AmpCs.



Check-Points Health
Binnenhaven 5
6709 PD Wageningen
The Netherlands

+31 (0) 317 453 908

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